If I install WordPress at [mydomain] - a domain that I keep hosted somewhere other than at Wordpress - will it interfere with any files I keep

• either on a dedicated subdomain (e.g. a bulletin board at forum.[mydomain])

• or in a subfolder (e.g. a collection of documents at [mydomain]/documents)?

I suspect the answer to the first part is "no", but I am not so sure about the second part, concerning the subfolder. I would like to save and remove files at [mydomain]/documents using FTP, and create other subfolders such as [mydomain]/whatever, without any relationship to or interference from WordPress or from what I do using Wordpress elsewhere on my site, but is that possible?